Recently, a lot of my patients have been asking about the newly
FDA-approved vuity eye drop made by Allergan. Vuity is a prescription eye
drop that contains 1.25% pilocarpine as its active ingredient.
FDA-approved vuity eye drop made by Allergan. Vuity is a prescription eye
drop that contains 1.25% pilocarpine as its active ingredient.
Mechanism of Vuity (Pilocarpine)
Pilocarpine temporarily improves near vision through two
mechanisms.
mechanisms.
Contents
1. Temporarily Stimulates Contraction of the Ciliar Body Muscle to shift
the eye into a more nearsighted state
First off, if your lenses still have any residual elasticity, Pilocarpine
will stimulate contraction of the ciliary body muscle to shift your eyes
into a more nearsighted state as I mentioned earlier, temporarily improving
near vision.
will stimulate contraction of the ciliary body muscle to shift your eyes
into a more nearsighted state as I mentioned earlier, temporarily improving
near vision.
2. Temporarily Constricts the Pupil and Creates a Pinhole Effect
The second and main way that vuity affects near vision is by stimulating
the parasympathetic muscles in the iris to constrict the pupil which creates
a pinhole effect. You may likely be experienced the pinhole effect yourself
when you go to your eye doctor’s office and have your vision checked with
one of these.
the parasympathetic muscles in the iris to constrict the pupil which creates
a pinhole effect. You may likely be experienced the pinhole effect yourself
when you go to your eye doctor’s office and have your vision checked with
one of these.
This is called an occluder. You may have noticed that when you look through
one of the small holes with the flap down, you see more clearly. This
phenomenon is called the pinhole effect.
one of the small holes with the flap down, you see more clearly. This
phenomenon is called the pinhole effect.
Pilocarpine constricts the pupil size causing a pinhole effect. Pilocarpine
was initially approved by the FDA in 1974 to treat glaucoma or to constrict
the pupil when needed for eye exams or eye surgeries.
was initially approved by the FDA in 1974 to treat glaucoma or to constrict
the pupil when needed for eye exams or eye surgeries.
Vuity (Pilocarpine) for Presbyopia
Vuity contains 1.25% pilocarpine and was recently approved by FDA in
October 2021 for the treatment for Presbyopia. It is dosed at one eye drop
in each eye once a day. According to the clinical trial data from the Gemini
1 and 2 studies, the effect of near vision improvement from vuity eye drop
can be seen as early as 15 minutes after applying the eye drop and can last
up to 6 to 10 hours.
October 2021 for the treatment for Presbyopia. It is dosed at one eye drop
in each eye once a day. According to the clinical trial data from the Gemini
1 and 2 studies, the effect of near vision improvement from vuity eye drop
can be seen as early as 15 minutes after applying the eye drop and can last
up to 6 to 10 hours.
Side Effects of Vuity Eye drop
However, there are some potential side effects of vuity in the Gemini 1 and
2 studies. Patients reported eye redness and headaches. Using vuity may also
decrease night vision by reducing the amount of light entering your eyes at
night through a small constricted pupil.
2 studies. Patients reported eye redness and headaches. Using vuity may also
decrease night vision by reducing the amount of light entering your eyes at
night through a small constricted pupil.
So you may need to be very careful when using it at night. Pilocarpine can
also rarely cause retinal detachment. So it is important to consult with
your eye doctor if you are considering using vuity.
also rarely cause retinal detachment. So it is important to consult with
your eye doctor if you are considering using vuity.
At the current time, vuity is not covered by most insurance and costs
about 75$ for each 2.5 ml bottle. As
vuity is newly approved for presbyopia we will likely learn more and
more about this medication as it becomes more widely available in the
US.
about 75$ for each 2.5 ml bottle. As
vuity is newly approved for presbyopia we will likely learn more and
more about this medication as it becomes more widely available in the
US.
0 Comments